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Advances in PH Journal

Pediatric Pulmonary Arterial Hypertension, Summer 2006 (Vol 5, No 2)
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  • Editor’s Memo
    Hands Across the Ocean: Building a Bridge to an International Pulmonary Hypertension Community
  • Profiles in Pulmonary Hypertension
    Sheila G. Haworth, MD, Creator of the UK Network for the Care of Children with Pulmonary Hypertension, Reviews Milestones in Clinical Management
  • Management of Idiopathic PAH in Children: Reexamining the Evolving Treatment Algorithm
    The treatment of pediatric idiopathic pulmonary arterial hypertension (IPAH) is challenging due to the serious nature of the disease, its rapid progression, and limited treatment options available for children. Similar to adults, IPAH in children is characterized by progressive elevation of the pulmonary arterial pressure leading to right ventricular failure and clinical deterioration if left untreated.
  • Persistent Pulmonary Hypertension of the Newborn: Pathophysiology and Treatment
    Survival at birth requires an immediate and sustained fall in pulmonary vascular resistance from its elevated level in utero to a low resistance, high flow circulation after delivery. This rapid drop allows for the eightfold increase in pulmonary blood flow that enables the lung to serve its postnatal function for gas exchange.
  • A Classification System and Treatment Guidelines for PAH Associated with Congenital Heart Disease
    Congenital heart defects are among the most common congenital malformations at birth, with an incidence of approximately 8/1000 live births. These defects are characterized by a heterogeneous group of abnormal communications and connections between the cardiac chambers and great vessels with different hemodynamic consequences and hence, varying need for follow-up and interventions.
  • Pulmonary Hypertension Roundtable
    Identifying the Complex Spectrum of Childhood PAH and Selecting Candidates for Aggressive Treatment