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Obesity is an important health issue in the United States and appears to have a significant impact on the disease course, as well as the response to therapy, in at least some patients with pulmonary arterial hypertension (PAH). Bariatric surgery represents a significant risk in patients with PAH; however, it may be a worthwhile consideration when non-surgical weight loss strategies and maximizing PAH therapies have not achieved treatment goals. This session will explore our limited understanding of the relationship between obesity and PAH and describe what the field has learned from previous cases of successful bariatric surgery in patients with PAH.
Variety is the Spice of Life: Combination Therapy for PAH
In this session we will discuss expert consensus guidelines for the use of combination therapy in PAH. We will briefly review the combination therapy clinical trial data to date including results of the recent AMBITION trial. We will also discuss some drug-drug interactions between PH medications.