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PHA Partners & Events

Right Heart Failure Summit (RHFS)

October 12 - 13, 2012

Boston Public Library
700 Boylston Street
Boston, MA 02116

Dear Colleague,

The right ventricle has suffered for much too long as an "orphan" but we now recognize that the sequelae of many conditions, such as pulmonary arterial hypertension, congenital heart disease and chronic left ventricular failure, are determined largely by their effects upon the right heart. In this regard, we bring you an international multidisciplinary conference to address the breadth and depth of this newly emerging focus in our Right Heart Failure Summit (RHFS) - to impart the scientific basis and clinical tools essential to understand and combat right heart disease.

The RHFS is an unprecedented expert forum – imparting incisive pathophysiological knowledge and real-world clinical strategies to optimally manage the effects of right heart failure stemming from multiple pathways, including pulmonary hypertension (both arterial and venous), adults with congenital heart disease (both uncorrected and repaired) and left heart failure (both as a consequence of the disease and in the setting of partial support as with a left ventricular assist device). A special feature will be to bring world experts in these different sentinel disorders to share their varied expertise and inform each other on optimal care for these patients.

I would like to bring to your attention several Key Note Features including a special Introduction by Dr. Eugene Braunwald (Distinguished Hersey Professor of Medicine, Harvard Medical School, Founding Chairman, TIMI Study Group, Brigham and Women's Hospital) and cutting edge lectures on Repairing and Growing New Lungs by Dr. Shaf Keshavjee (Surgeon-in-Chief, Director, Toronto Lung Transplant Program, Toronto, Canada) and unique innovative transcatheter approaches to rescuing the right heart failure by Dr. James Lock (Chairman, Department of Cardiology, Boston Children's Hospital, Alexander S. Nadas Professor of Pediatrics).

In addition, you will have the opportunity to:

  • Collaborate with our expert faculty to decipher the most recent clinical data and the immediate implications for your patients and practice.
  • Access evidence-based solutions for managing complex patients with multiple manifestations of right heart disease.
  • Discuss pearls in clinical management using real-world cases.

Please join us, along with many world-renowned expert faculty in the historical setting of the Boston Public Library in one of the world's most beautiful cities.

We look forward to your participation at the 2012 program in Boston! The link to the program for information and registration is:

http://www.medfound.com/rhfs/index.html

Sincerely,

Program Chair:

Mandeep R. Mehra, MBBS, FACC, FACP

Professor of Medicine
Harvard Medical School
Executive Director
Center for Advanced Heart Disease
Brigham and Women's Hospital
Boston, Massachusetts
Editor-in-Chief
The Journal of Heart and Lung Transplantation

Program Co-Chair:

Myung H. Park, MD, FACC

Associate Professor of Medicine
Director, Pulmonary Vascular Disease Program
University of Maryland Division of Cardiology
Baltimore, Maryland

Section Co-Chairs:

Michael J. Landzberg, MD

Assistant Professor of Medicine
Harvard Medical School
Director, Boston Adult Congenital Heart (BACH) and Pulmonary Hypertension Program
Boston, Massachusetts          

Aaron B. Waxman, MD, PhD

Director, Pulmonary Vascular Disease Program
Brigham and Women's Hospital
Associate Professor of Medicine
Harvard Medical School
Boston, Massachusetts

 

AGENDA

FRIDAY, OCTOBER 12th

7:20 am:   Breakfast and Registration

8:05 am:   Opening Remarks Dr. Mandeep R. Mehra and Dr. Myung H. Park

8:10 am:   Welcome Address Dr. Elizabeth G. Nabel

8:20 am:   Introductory Remarks Dr. Eugene Braunwald

Session I. RV Structure and Function: From Health To Disease

Chairs:  Dr. Mandeep R. Mehra and Dr. Eugene Braunwald

8:30 am:   Anatomy and Embryology:  Differentiating RV from LV Dr. Tal Geva

8:50 am:   RV / PA Coupling: Structure / Function Paradox Dr. Robert Naeije

9:10 am:   How Do You Visualize the RV? Imaging Modalities (cMRI, CT, Echo) Dr. Anton Vonk Noordegraaf

9:30 am:   Metabolic Demands and Function of the RV: Utility of PET Dr. Martin Wilkins

9:50 am:   Panel Discussion / Q&A  All Faculty

10:10 am:  Break

Session II. Insights from Congenital Heart Disease

Chairs: Dr. Curt Daniels and Dr. Michael J. Landzberg

10:30 am:  Interventricular Dependence: Insights from “Pre-tricuspid” Shunts Dr. Steven D. Colan

10:50 am:  Tetralogy of Fallot: How the RV and the Pulmonary Vasculature Fail….and Heal Dr. Michael J. Gatzoulis

11:10 am:  Eisenmenger Syndrome:  Lessons from an Unusual Model of Cardio-vascular Cross-talk and Vascular Healing Dr. Alexander Opotowsky

11:30 am:  Pulmonary Veins in Congenital Heart Disease Dr. Mary Mullen

11:50am:  Panel Discussion / Q&A  All Faculty

12:10 pm:  Lunch

1:00pm:  Special Lecture:  Brave New World – Building a New Lung Dr. Shaf Keshavjee 

Session III.Response of RV to Pulmonary Arterial Hypertension

Chairs: Dr. Myung H. Park and Dr. Aaron B. Waxman

2:00 pm:   RV Adaptation to Pulmonary Hypertension: Insights from Exercise Physiology Dr. David Systrom

2:20 pm:   Contemporary PAH Directed Therapies: Targets and Outcomes Dr. Vallerie V. McLaughlin

2:40 pm:   The Impact of Comorbidities on Pulmonary Vasculature: Sleep Disordered Breathing and Obesity Dr. Nicholas S. Hill

3:00 pm:   Systemic Disorders and Pulmonary Arterial Hypertension: Unique Aspects  Dr. Jean-Luc Vachiery

3:20 pm:   Panel Discussion / Q&A  All Faculty

3:45 pm:   Adjourn for the Day

SATURDAY, OCTOBER 13th

7:45 am Breakfast and Registration

Session IV. Surgical / Innovative Approaches to RV Failure

Chairs:  Dr. James E. Lock and Dr. Robert L. Kormos

8:30 am:    Special Lecture: Novel Shunts and Innovative Approaches Dr. James E. Lock

9:10 am:   The Make-up of RV Afterload Dr. Andrew Reddington

9:30 am:   RVADs / ECMO:  Realistic Possibilities Dr. Robert L. Kormos

9:50 am:    Medical and Surgical Concepts in Chronic Thromboembolic PH Dr. William Auger

10:10 am:  Novel Molecules and Targets for Pulmonary Vascular Disease Dr. Nicholas Morrell

10:30 am:  Panel Discussion / Q&A  All Faculty

10:50 am:  Break

11:10 am:  How To Workshops (Select Stream I or Stream II)

Stream I: How to Pearls in Pulmonary Hypertension

Chairs: Dr. Raymond L. Benza and Dr. Hunter Champion

11:10  am: Case I: Use and Abuse of Hemodynamics and Imaging in PH Dr. Paul R. Forfia

11:25 am:  Case II: Left Heart Disease and PH Dr. Robert P. Frantz

11:40 am: Case III: Primary Lung Disease and PH Dr. Ivan M. Robbins

11:55 am: Case IV: Complexities of PH Therapy Dr. Patricia A. Uber

12:10 pm: Panel Discussion / Q&A All Faculty

12:30 pm: Closing Remarks
 

Stream II: How To Pearls in Adult Congenital Heart Disease

Chairs: Dr. Maurice Beghetti and Dr. Alexander Opotowsky

11:10  am:Case I: Treatment Considerations in PH and CHD related PH Dr. Richard A. Krasuski

11:25 am:  Case II: Eisenmenger:  Options to Consider / Pitfalls to Avoid Dr. Gary Webb

11:40 am:  Case III:  Severe PAH Associated with Systemic Arterial to PA Shunts:  When, If Ever, to Consider Surgical Shunt Closure Dr. Maurice Beghetti

11:55 am:  Case IV: CHD Hemodynamics: Bring it on!  Dr. Michael J. Landzberg

12:10 pm:  Panel Discussion / Q&A All Faculty 

12:30 pm:  Closing Remarks

12:45 pm:  Program Adjournment and Lunch

 

After completing this activity, the participant should be able to:
  1.   Describe the unique structure and function of the right ventricle (RV) with focus on anatomical and embryological differences between the RV and LV
  2.   Review current understanding regarding the importance of RV and Pulmonary Arterial coupling and its role in RV function and RV failure
  3.   Summarize the emerging role of cMRI and 3D echocardiography imaging in assessing RV function
  4.   Discuss the current data regarding myocardial metabolism and RV function
  5.   Describe RV adaptation and maladaptation in pulmonary arterial hypertension (PAH)
  6.   Assess the effectiveness and adequacy of current therapies used in management of PAH
  7.   Discuss the impact of cardio-metabolic risk factors and sleep disordered breathing in RV failure
  8.   Learn the most up to date epidemiological and treatment strategies in PAH associated with systemic disorders
  9.   Discuss novel molecular pathways and emerging therapies in PAH
  10.   Understand the importance of peripheral mechanisms in the pathology and physiology of adults with congenital heart disease (CHD)
  11.   Learn to evaluate and manage adults with repaired congenital heart defects
  12.   Identify patients at increased risk for cardiac comorbidities due to the presence of CHD.
  13.   Given a patient with CHD-associated PH, select an appropriate therapy to fit the patient's individualized circumstances according to the latest scientific evidence.
  14.   Describe interventional cardiovascular repair techniques for CHD.
  15.   Discuss the pharmacological and non-pharmacologic management of the critically ill patient with pulmonary hypertension crisis and shock from right heart failure
  16.   Discuss appropriate management and treatment for patients with chronic thromboembolic pulmonary hypertension
  17.   Discuss emerging role of surgical mechanical support for RV failure, from RVADS to ECMO
  18.   Discuss the role of the community specialist in the continuum of care for patients with congenital heart disease, heart failure and pulmonary arterial hypertension.

More Information: http://www.medfound.com/rhfs/index.html