Advances in Pulmonary Hypertension Autumn 2007 (Vol 6, No 3)
Guest Editor’s Commentary Focusing on Pulmonary Arterial Hypertension in Adults with Congenital Heart Disease
Editor's Memo Another Milestone for PHA Mission to Promote Awareness
Profiles in PH: Joseph K. Perloff, MD: Father of Adult Congenital Heart Disease
Pulmonary Arterial Hypertension in Adults with Congenital Heart Disease: General Overview of Disease Mechanisms Adults with congenital heart disease (CHD) have become a rapidly expanding group of complex patients requiring multidisciplinary care in specialty centers by those trained in CHD. They represent one of the most challenging subgroups of patients with pulmonary arterial hypertension (PAH) due to the presence of structural heart disease with or without coexisting cyanosis and its complications.
Emerging Therapy of Congenital Heart Disease Associated with Pulmonary Hypertension Pulmonary arterial hypertension associated with congenital heart disease (CHD-PAH), as discussed throughout this issue of Advances in Pulmonary Hypertension, is one of the most commonly occurring causes of significant or severe morbidity and untimely mortality in CHD patients.1 Without surgical therapy, it is suggested that some 30% of CHD patients will develop PAH
